California Research Foundation

Dedicated to Excellence in Medical Research Since 1966

Our Mission

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California Research Foundation (CRF) has been a leader in clinical trials since 1966, performing hundreds of protocols covering most areas of Internal Medicine. CRF is a multi-specialty group of private practice Board-Certified specialists supported by a full-time staff dedicated solely to clinical research. California Research Foundation has completed over 500 FDA sanctioned clinical investigative studies covering all phases, with enrollment totals of up to 1000 patients.

California Research Foundation has experience in many disciplines and has helped advance science and bring to market many novel medications. CRF takes great pleasure in knowing that our work has played at least a small part in preventing disease and helping improve the lives of so many people who suffer from chronic conditions such as Arthritis, Diabetes, Hypertension, and Osteoporosis to name a few.

Healthy volunteer and vaccine studies are a specialty and the CRF Vaccine Unit has over 20 years of experience performing geriatric, adult, and pediatric vaccine protocols, including vaccines for COVID-19, Influenza, Pandemic Flu, H1N1 Flu (Swine), H5N1 & H5N6 Flu (Avian), Meningitis, Dengue Fever, HPV, CMV, Pneumonia, RSV and more.

During the worldwide COVID-19 pandemic, CRF earned the honor of being recognized as one of the top three sites in the world for their work on Pfizer's landmark COVID-19 vaccine protocol, the first COVID-19 vaccine approved for emergency use in the United States and the first FDA approved COVID-19 vaccine in the United States. We consider this recognition a salute to our dedicated and committed research staff and the real heroes of the pandemic - the study volunteers who stood up during this worldwide emergency and selflessly offered to join the effort to find a safe and effective vaccine to counter a virus that was affecting everyone around the world.

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